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Parkinson's disease: cause discovered: Researchers at the Hertie Institute for Clinical Brain Research at the University of Tübingen have discovered two proteins that play a role in the development of Parkinson's disease.
Dr. Wolfdieter Springer, Prof. Dr. Philipp Kahle and colleagues have now published the results of their study in the specialist journal "Nature Cell Biology". The two crucial proteins were found in the area of the mitochondria. The latter are the “power plants” of our cells by providing energy in the form of ATP (adenosine triphosphate).
If a mitochondrion is defective or destroyed, it becomes a "troublemaker" in the cell and has to be disposed of. To do this, it is labeled by the two proteins mentioned (Parkin and PINK-1) with another protein (ubiquitin). This marker is the signal to the cell to dispose of said mitochondrion. In Parkinson's disease, this marking and disposal does not seem to work.
This could offer new possibilities for therapy in the future by helping the organism to compensate for the two substances or by finding ways why this mechanism is disturbed. (Thorsten Fischer, naturopath osteopathy, 02/01/2010)
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